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Accession: PRJNA473130 ID: 473130

RNA transcriptome analysis of IRF1 and IRF3 knockout in immortalized primary hepatocytes infected with hepatitis A virus (human)

See Genome Information for Homo sapiens
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66643 additional projects are related by organism.
Interferon regulatory factors (IRFs) play key roles in the transactivation of antiviral genes at the step downstream of activated pathogen-associated molecular pattern sensors, such as RIG-I-like receptors or Toll-like receptors. More...
AccessionPRJNA473130; GEO: GSE114916
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsYamane D et al., "Basal expression of interferon regulatory factor 1 drives intrinsic hepatocyte resistance to multiple RNA viruses.", Nat Microbiol, 2019 Jul;4(7):1096-1104
SubmissionRegistration date: 25-May-2018
Lemon Lab, Division of Infectious Diseases, University of North Carolina at Chapel Hill
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments12
Publications
PubMed1
PMC1
Other datasets
BioSample12
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes1
SRA Data Details
ParameterValue
Data volume, Gbases44
Data volume, Mbytes26231

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