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Genome Information for Saccharomyces cerevisiae
We have identified mRNAs whose abundance or translational efficiency is regulated in nutrient-rich medium by the Scd6 or Dhh1 protein in either wild-type cells or dcp2∆ cells lacking the decapping enzyme
Overall design: Ribosome profiling and RNA-seq was conducted to determine changes in mRNA abundance, translation, or translational efficiecies in comparing scd6∆ or dhh1∆ mutants to an isogenic wild-type strain; or scd6∆dcp2∆ and dhh1∆dcp2∆ strains to a dcp2∆ mutant
| Accession | PRJNA472988; GEO: GSE114892 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Saccharomyces cerevisiae[Taxonomy ID: 4932] Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae |
| Publications | Zeidan Q et al., "Conserved mRNA-granule component Scd6 targets Dhh1 to repress translation initiation and activates Dcp2-mediated mRNA decay in vivo.", PLoS Genet, 2018 Dec;14(12):e1007806 |
| Submission | Registration date: 24-May-2018
Gene Regulation and Development, NICHD, NIH |
| Relevance | Model Organism |
Project Data:
| Resource Name | Number
of Links |
|---|
| Sequence data |
| SRA Experiments | 28 |
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| BioSample | 28 |
| GEO DataSets | 1 |