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Accession: PRJNA472802 ID: 472802

Genome wide chromatin accessibilty changes associated with JUN expression in human normal and IPF lung fiborblasts (human)

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We found that JUN expression is increased in many human fibrotic diseases and that systemic induction of Jun in mice resulted in development of fibrosis of multiple organs. More...
AccessionPRJNA472802; GEO: GSE114844
Data TypeEpigenomics
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsCui L et al., "Activation of JUN in fibroblasts promotes pro-fibrotic programme and modulates protective immunity.", Nat Commun, 2020 Jun 3;11(1):2795
SubmissionRegistration date: 23-May-2018
Gerlinde Wernig Lab, Pathology, Institute for Regenerative Medicine and Stem Cell Research, Stanford University School of Medicine
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments12
Publications
PubMed1
PMC1
Other datasets
BioSample12
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes4976
SRA Data Details
ParameterValue
Data volume, Gbases73
Data volume, Mbytes28347

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