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Accession: PRJNA472726 ID: 472726

Gene expression signatures of Naïve vs Revertant CD8 T cells from human cord blood (human)

See Genome Information for Homo sapiens
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66643 additional projects are related by organism.
We have employed whole genome microarray expression profiling as a discovery platform to identify genes with the potential to distinguish between naive CD8+ T cells (TN) and the same cells which, after activation and incubation with homeostatic cytokines, had reverted to a naive-like phenotype (TNrev). More...
AccessionPRJNA472726; GEO: GSE114812
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
Publications
  • Frumento G et al., "Homeostatic Cytokines Drive Epigenetic Reprogramming of Activated T Cells into a "Naive-Memory" Phenotype.", iScience, 2020 Apr 24;23(4):100989
  • Frumento G et al., "CD117 (c-Kit) Is Expressed During CD8+ T Cell Priming and Stratifies Sensitivity to Apoptosis According to Strength of TCR Engagement.", Front Immunol, 2019;10:468
SubmissionRegistration date: 23-May-2018
Moss, Immunology and Immunotherapy, University of Birmingham
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Publications
PubMed2
PMC2
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots352302
Data volume, Processed Mbytes6
Data volume, Supplementary Mbytes19

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