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Accession: PRJNA471740 ID: 471740

Determination of global decay rates of yeast transcriptome and identification of factors impact mRNA stability (baker's yeast)

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4197 additional projects are related by organism.
In this work, we determine total mRNA decay rates in rpb1-1 and rpb1-1/caf1∆ cells, calculate half-lives in rpb1-1/caf1∆ cells relative to rpb1-1 cells and correlate them with codon optimality. More...
AccessionPRJNA471740; GEO: GSE114560
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismSaccharomyces cerevisiae[Taxonomy ID: 4932]
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces; Saccharomyces cerevisiae
PublicationsWebster MW et al., "mRNA Deadenylation Is Coupled to Translation Rates by the Differential Activities of Ccr4-Not Nucleases.", Mol Cell, 2018 Jun 21;70(6):1089-1100.e8
Grants
  • "Determining the influence of codon optimality on mRNA translation and decay" (Grant ID R01 GM118018, National Institute of General Medical Sciences)
  • "Understanding the Interconnection Between mRNA turnover and mRNA Translation" (Grant ID R01 GM125086, National Institute of General Medical Sciences)
SubmissionRegistration date: 16-May-2018
Center for RNA Science and Therapeutics, Case Western Reserve University
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments10
Publications
PubMed1
PMC1
Other datasets
BioSample10
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes1
SRA Data Details
ParameterValue
Data volume, Gbases25
Data volume, Mbytes17565

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