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Accession: PRJNA471071 ID: 471071

Enzyme promiscuity shapes evolutionary innovation and optimization

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A computational model of underground metabolism and laboratory evolution experiments were employed to examine the role of enzyme promiscuity in the acquisition and optimization of growth on predicted non-native substrates in E. More...
AccessionPRJNA471071; GEO: GSE114358
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismEscherichia coli str. K-12 substr. MG1655[Taxonomy ID: 511145]
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia; Escherichia coli; Escherichia coli str. K-12 substr. MG1655
PublicationsGuzmán GI et al., "Enzyme promiscuity shapes adaptation to novel growth substrates.", Mol Syst Biol, 2019 Apr 8;15(4):e8462
SubmissionRegistration date: 11-May-2018
Palsson Lab, Bioengineering, University of California, San Diego
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments22
Publications
PubMed1
PMC1
Other datasets
BioSample22
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes3
SRA Data Details
ParameterValue
Data volume, Gbases6
Data volume, Mbytes2695

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