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Accession: PRJNA470944 ID: 470944

Effect of Ro 08-2750 treatment on gene expression of human leukemia cell lines MOLM13 and K562 (human)

See Genome Information for Homo sapiens
RNA-sequencing on human leukemia cell lines MOLM13 (AML, MLL-AF9+) and K562 (CML-BC, BCR-ABL+) after Ro 08-2750 treatment (20 uM, 4hours) Overall design: Cells were cultured at 0.5M/mL and treated with the small-molecule Ro 08-2750 for 4hours at 20 uM
AccessionPRJNA470944; GEO: GSE114320
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsMinuesa G et al., "Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia.", Nat Commun, 2019 Jun 19;10(1):2691
SubmissionRegistration date: 10-May-2018
Kharas Laboratory, Molecular Pharmacology, Memorial Sloan Kettering Cancer Center
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments16
Publications
PubMed1
PMC1
Other datasets
BioSample16
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes1
SRA Data Details
ParameterValue
Data volume, Gbases25
Data volume, Mbytes13689

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