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Accession: PRJNA470767 ID: 470767

Selective Targeting of PARP2 Inhibits Androgen Receptor Signaling and Prostate Cancer Growth Through Disruption of FOXA1 Function

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series
AccessionPRJNA470767; GEO: GSE114275
TypeUmbrella project
PublicationsGui B et al., "Selective targeting of PARP-2 inhibits androgen receptor signaling and prostate cancer growth through disruption of FOXA1 function.", Proc Natl Acad Sci U S A, 2019 Jul 16;116(29):14573-14582
SubmissionRegistration date: 10-May-2018
Thorn 1529, Surgery, Brigham and Women's Hospital
RelevanceSuperseries
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments31
Publications
PubMed1
PMC1
Other datasets
BioSample31
GEO DataSets3
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes2897
SRA Data Details
ParameterValue
Data volume, Gbases75
Data volume, Mbytes31404
Selective Targeting of PARP2 Inhibits Androgen Receptor Signaling and Prostate Cancer Growth Through Disruption of FOXA1 Function encompasses the following 2 sub-projects:
Project TypeNumber of Projects
Epigenomics1
BioProject
accession
OrganismTitle
PRJNA471000Homo sapiensGenome-wide occupation of AR, FOXA1, and H3K27AC in LNCaP cells treated with selective PARP2 inhibitor UPF-1069 (Thorn 1529, Surgery, Brigham...)
Transcriptome or Gene expression1
BioProject
accession
OrganismTitle
PRJNA471001Homo sapiensGene expression profilings for prostate cancer cells after inhibition of PARP1 or PARP2 using pharmaceutical or siRNA-based approaches (Thorn 1529, Surgery, Brigham...)

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