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Accession: PRJNA470688 ID: 470688

Effect of estrogen (E2) treatment on the C4-12 relative to the MCF7 cells (human)

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To confirm the effect of estrogen, through the estrogen receptor, on cell cycle progression and to identify the key molecules that play an important role in this regulation, MCF-7aro (ER+ cell line) and C4-12ERaERE (ER lacking cell line stably transfected with ERaERE) were used for RNAseq analysis. More...
AccessionPRJNA470688; GEO: GSE114260
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsPetrossian K et al., "ERα-mediated cell cycle progression is an important requisite for CDK4/6 inhibitor response in HR+ breast cancer.", Oncotarget, 2018 Jun 12;9(45):27736-27751
SubmissionRegistration date: 9-May-2018
KCRB 2018, Cancer Biology, Beckman Research Institute at City of Hope
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments6
Publications
PubMed1
PMC1
Other datasets
BioSample6
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes2
SRA Data Details
ParameterValue
Data volume, Gbases14
Data volume, Mbytes4756

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