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Accession: PRJNA393591 ID: 393591

Mus musculus (house mouse)

Dynamic regulation of T Follicular Regulatory (Tfr) cell responses by IL-2 during influenza infection

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47588 additional projects are related by organism.
We found that approximately 2,000 genes were differentially expressed between conventional Treg and Tfr cells following influenza virus infection Overall design: We conducted an RNA-seq analysis on sorted conventional Treg cells (FoxP3+CD69hiPD1loCXCR5loCD25hi) and Tfr cells (FoxP3+CD69hiPD1hiCXCR5hiCD25lo) obtained from the mediastinal lymph node (mLN) of day 30 infected B6. More...
AccessionPRJNA393591; GEO: GSE101016
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsBotta D et al., "Dynamic regulation of T follicular regulatory cell responses by interleukin 2 during influenza infection.", Nat Immunol, 2017 Nov;18(11):1249-1260
SubmissionRegistration date: 9-Jul-2017
SHEL413, Medicine, Division of Clinical Immunology and Rheumatology, The University of Alabama at Birmingham
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments6
Publications
PubMed1
PMC1
Other datasets
BioSample6
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes31
SRA Data Details
ParameterValue
Data volume, Gbases7
Data volume, Mbytes2487

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