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2 additional projects are components of the Identification of symmetric methylation of histone H4 arginine 3 on KSHV genome.
The objective of this study was to identify the symmetric methylation sites on KSHV genome during latency and lytic reactivation
Overall design: KSHV infected, TRExBCBL1-RTA or iSLKBac16WT cells were induced with doxycycline for 12h or 24h to trigger the lytic reactivation, cells were crosslinked and subjected for chromatin isolation and sonication. ChIP assay was performed using specific antibodies.
| Accession | PRJNA383839; GEO: GSE98057 |
| Data Type | Epigenomics |
| Scope | Multiisolate |
| Organism | Human gammaherpesvirus 8[Taxonomy ID: 37296] Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes; Herpesvirales; Orthoherpesviridae; Gammaherpesvirinae; Rhadinovirus; Rhadinovirus humangamma8; Human gammaherpesvirus 8 |
| Publications | Strahan RC et al., "KSHV encoded ORF59 modulates histone arginine methylation of the viral genome to promote viral reactivation.", PLoS Pathog, 2017 Jul;13(7):e1006482 |
| Submission | Registration date: 21-Apr-2017
Verma Lab, Microbiology and Immunology, University of Nevada, Reno |
| Relevance | Unknown |
Project Data:
| Resource Name | Number
of Links |
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| Sequence data |
| SRA Experiments | 10 |
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| BioSample | 10 |
| GEO DataSets | 1 |