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Accession: PRJNA344730 ID: 344730

Enhancer Remodeling During Adaptive Bypass to MEK Inhibition Is Attenuated by Pharmacological Targeting of the P-TEFb Complex

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series
AccessionPRJNA344730; GEO: GSE87424
TypeUmbrella project
PublicationsZawistowski JS et al., "Enhancer Remodeling during Adaptive Bypass to MEK Inhibition Is Attenuated by Pharmacologic Targeting of the P-TEFb Complex.", Cancer Discov, 2017 Mar;7(3):302-321
SubmissionRegistration date: 28-Sep-2016
Gary L. Johnson Lab, Pharmacology, University of North Carolina School of Medicine
RelevanceSuperseries
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments127
Publications
PubMed1
PMC1
Other datasets
BioSample155
GEO DataSets6
GEO Data Details
ParameterValue
Data volume, Spots5826924
Data volume, Processed Mbytes118
Data volume, Supplementary Mbytes347
SRA Data Details
ParameterValue
Data volume, Gbases374
Data volume, Mbytes86428
Enhancer Remodeling During Adaptive Bypass to MEK Inhibition Is Attenuated by Pharmacological Targeting of the P-TEFb Complex encompasses the following 5 sub-projects:
Project TypeNumber of Projects
Epigenomics2
BioProject
accession
OrganismTitle
PRJNA343728Homo sapiensEnhancer Remodeling During Adaptive Bypass to MEK Inhibition Is Attenuated by Pharmacological Targeting of the P-TEFb Complex (DNA methylation) (Gary L. Johnson Lab, Pharmacology,...)
PRJNA344724Homo sapiensEnhancer Remodeling During Adaptive Bypass to MEK Inhibition Is Attenuated by Pharmacological Targeting of the P-TEFb Complex (ChIP-seq) (Gary L. Johnson Lab, Pharmacology,...)
Transcriptome or Gene expression2
BioProject
accession
NameTitle
PRJNA344725Enhancer Remodeling During Adaptive Bypass to MEK Inhibition Is Attenuated by Pharmacological Targeting of the P-TEFb Complex (RNA-seq)Enhancer Remodeling During Adaptive Bypass to MEK Inhibition Is Attenuated by Pharmacological Targeting of the P-TEFb Complex (RNA-seq) (Gary L. Johnson Lab, Pharmacology,...)
PRJNA420378Homo sapiensDefining the Triple Negative Breast Cancer Kinome Response to GSK1120212 (RNA-Seq) (Gary L. Johnson Lab, Pharmacology,...)
Variation1
BioProject
accession
OrganismTitle
PRJNA344764Homo sapiensEnhancer Remodeling During Adaptive Bypass to MEK Inhibition Is Attenuated by Pharmacological Targeting of the P-TEFb Complex (Exome-seq) (Gary L. Johnson Lab, Pharmacology,...)

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