See
Genome Information for Homo sapiens
genomic analysis using arrayCGH to gain insight into chromosomal copy number in mucoepidermoid carcinoma (MEC). Results suggest that two types of MECs can be distinguished: (i) a group of MECs without t(11;19)(q21;p13) translocation with many copy number aberrations (> 6), independent of histological grade, and (ii) a group of MECs with the t(11;19)(q21;p13) translocation with no or a few copy number aberrations (<6 ) with two exceptions classified as low and intermediate grade.
Overall design: Tumor DNA vs Normal DNA from surrounding tumor tissue. 27 parrafine embedded MEC samples of which 17 low grade, 6 intermediate grade and 4 high grade MEC samples were compared to normal surrounding tissue.
| Accession | PRJNA344477; GEO: GSE87353 |
| Data Type | Variation |
| Scope | Multiisolate |
| Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
| Publications | Matse JH et al., "High number of chromosomal copy number aberrations inversely relates to t(11;19)(q21;p13) translocation status in mucoepidermoid carcinoma of the salivary glands.", Oncotarget, 2017 Sep 19;8(41):69456-69464 |
| Submission | Registration date: 26-Sep-2016
Department of Oral and Maxillofacial Surgery and Oral Pathology, VU University medical center |
| Relevance | Medical |
Project Data:
| Resource Name | Number
of Links |
|---|
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| GEO DataSets | 1 |
GEO Data Details| Parameter | Value |
|---|
| Data volume, Spots | 4695786 |
| Data volume, Processed Mbytes | 53 |
| Data volume, Supplementary Mbytes | 511 |