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Accession: PRJNA343797 ID: 343797

Homo sapiens (human)

LaminB1 DamID in HT1080 fibroblasts overexpressing NET29/TMEM120A, NET39/PPAPDC3 or NET47/TM7SF2

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This project is a component of the Transcriptional and genome organization changes in HT1080 cells after overexpression of tissue-specific nuclear transmembrane proteins (NETs)
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1 additional project is a component of the Transcriptional and genome organization changes in HT1080 cells after overexpression of tissue-specific nuclear transmembrane proteins (NETs).
66644 additional projects are related by organism.
Maps of genomic regions in proximity to the nuclear lamina were determined in untreated HT1080 fibroblasts and HT1080 stable cell lines expressing NET29/TMEM120A, NET39/PPAPDC3 or NET47/TM7SF2 as GFP fusions Overall design: The nuclear transmembrane proteins (NETs) NET29/TMEM120A, NET39/PPAPDC3 and NET47/TM7SF2 are able to reposition chromosomes towards/away from the nuclear envelope when overexpressed or knocked down in HT1080 cells. More...
AccessionPRJNA343797; GEO: GSE87148
Data TypeEpigenomics
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
Publicationsde Las Heras JI et al., "Tissue-specific NETs alter genome organization and regulation even in a heterologous system.", Nucleus, 2017 Jan 2;8(1):81-97
SubmissionRegistration date: 20-Sep-2016
Swann 5.12, Wellcome Trust Centre, University of Edinburgh
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments8
Publications
PubMed1
PMC1
Other datasets
BioSample8
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes298
SRA Data Details
ParameterValue
Data volume, Gbases61
Data volume, Mbytes51885

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