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Accession: PRJNA343643 ID: 343643

Mus musculus (house mouse)

Transcriptional profiling of Regulatory T-cells isolated from neonatal skin and skin draining lymph nodes (SDLNs)

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47588 additional projects are related by organism.
Purpose: The goals of this study were to identify preferential gene expression signatures that are unique to Tregs in neonatal skin relative to peripheral Tregs Methods: Tregs from telogen skin and SDLNs were purified by cell sorting (using the Treg GFP reporter mouse line Foxp3-DTR/GFP) to generate mRNA transcription profiles. More...
AccessionPRJNA343643; GEO: GSE87130
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsScharschmidt TC et al., "Commensal Microbes and Hair Follicle Morphogenesis Coordinately Drive Treg Migration into Neonatal Skin.", Cell Host Microbe, 2017 Apr 12;21(4):467-477.e5
Grants
  • "Elucidating mechanisms of tolerance to commensal skin bacteria" (Grant ID K08 AR068409, National Institute of Arthritis and Musculoskeletal and Skin Diseases)
SubmissionRegistration date: 20-Sep-2016
Dermatology, University of California, San Francisco
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments5
Publications
PubMed1
PMC1
Other datasets
BioSample5
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes1
SRA Data Details
ParameterValue
Data volume, Gbases14
Data volume, Mbytes9192

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