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Accession: PRJNA343235 ID: 343235

Homo sapiens (human)

A total RNA-Seq screen reveals that the splicing inhibitor Isoginkgetin blocks transcription elongation

See Genome Information for Homo sapiens
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66644 additional projects are related by organism.
Pharmacological perturbation is a powerful tool for understanding gene expression, but identification of the specific steps of this multi-step process targeted by small molecules remains challenging. More...
AccessionPRJNA343235; GEO: GSE86857
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsBoswell SA et al., "Total RNA-seq to identify pharmacological effects on specific stages of mRNA synthesis.", Nat Chem Biol, 2017 May;13(5):501-507
SubmissionRegistration date: 13-Sep-2016
Gray lab, Genetics, Harvard Medical School
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments80
Publications
PubMed1
PMC1
Other datasets
BioSample80
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes219
SRA Data Details
ParameterValue
Data volume, Gbases103
Data volume, Mbytes47985

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