BioProject

Wild derived mouse inbred strains are becoming increasing popular for complex traits analysis, evolutionary studies, and systems genetics. More...

Wild derived mouse inbred strains are becoming increasing popular for complex traits analysis, evolutionary studies, and systems genetics. Here we report the whole-genome sequencing of two wild derived mouse inbred strains, LEWES/EiJ and ZALENDE/EiJ, of Mus musculus domesticus origin. These two inbred strains were selected based on their geographic origin, karyotype, and use in ongoing research. We generated 14X and 18X coverage sequence and discovered 0.4 and 0.6 M novel variants relative to the mm10 reference genome, respectively. This report expands the number of wild derived inbred genomes in Mus genus from six to eight. The sequence variation can be accessed via a query tool; variant calls (VCF format) and alignments (BAM format) are available for download from a dedicated ftp site; and the sequencing data has also been stored in a lossless, compressed, indexed format using the multi-string Burrows-Wheeler transform (URL). All data can be used without restriction. Less...