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Accession: PRJNA342809 ID: 342809

Mus musculus (house mouse)

Transcriptional repression by non-canonical EED stimulation of histone deacetylase activity is required for heart maturation independently of H3K27me3 [RNA-seq]

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This project is a component of the EED orchestration of heart maturation through interaction with HDACs is H3K27me3-independent
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3 additional projects are components of the EED orchestration of heart maturation through interaction with HDACs is H3K27me3-independent.
47588 additional projects are related by organism.
Through H3K27me3 and H3K27ac ChIP-seq and microarray data in wile-tpye (WT) and EED-knockout (CKO) mouse cardiomyocytes, we unexpectedly uncovered a novel mechanism of PRC2-mediated gene repression. More...
AccessionPRJNA342809; GEO: GSE86868
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsAi S et al., "EED orchestration of heart maturation through interaction with HDACs is H3K27me3-independent.", Elife, 2017 Apr 10;6
SubmissionRegistration date: 13-Sep-2016
Aibin He, Academy for Advanced Interdisciplinary Studies, Institute of Molecular Medicine, Peking-Tsinghua Center for Life Sciences, Peking University
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments4
Publications
PubMed1
PMC1
Other datasets
BioSample4
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes225
SRA Data Details
ParameterValue
Data volume, Gbases14
Data volume, Mbytes9823

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