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Accession: PRJNA342608 ID: 342608

Homo sapiens (human)

Assessing the impact of loss of ATF7IP and SETDB1 on the transcriptome

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This project is a component of the ATF7IP-mediated stabilization of the histone methyltransferase SETDB1 is essential for heterochromatin formation by the HUSH complex
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1 additional project is a component of the ATF7IP-mediated stabilization of the histone methyltransferase SETDB1 is essential for heterochromatin formation by the HUSH complex.
66644 additional projects are related by organism.
By comparing HeLa cells lacking ATF7IP or SETDB1 generated through CRISPR/Cas9-mediated gene disruption to wild-type HeLa cells, the goal of the experiment was to determine the effect of loss of the SETDB1•ATF7IP complex on the transcriptome. More...
AccessionPRJNA342608; GEO: GSE86813
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsTimms RT et al., "ATF7IP-Mediated Stabilization of the Histone Methyltransferase SETDB1 Is Essential for Heterochromatin Formation by the HUSH Complex.", Cell Rep, 2016 Oct 11;17(3):653-659
SubmissionRegistration date: 12-Sep-2016
Lehner Lab, 5.19, Cambridge Institute for Medical Research, University of Cambridge
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments9
Publications
PubMed1
PMC1
Other datasets
BioSample9
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes1
SRA Data Details
ParameterValue
Data volume, Gbases42
Data volume, Mbytes26474

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