See
Genome Information for Mus musculus
Current systems for conditional gene deletion within mouse macrophage lineages are limited by ectopic activity or low efficiency; we generated a Mafb-driven Cre strain to determine whether any dendritic cells (DCs) identified by Zbtb46-GFP expression originate from a Mafb-expressing population
Overall design: Ly-6C(hi) monocytes, Ly-6C(lo) YFP(-) monocytes, and Ly-6C(lo) YFP(+) monocytes were isolated by FACS from blood samples harvested from MafB-mCherry-Cre x R26-stop-YFP x Zbtb46-GFP lineage-tracing mice
| Accession | PRJNA342324; GEO: GSE86596 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus |
| Publications | Wu X et al., "Mafb lineage tracing to distinguish macrophages from other immune lineages reveals dual identity of Langerhans cells.", J Exp Med, 2016 Nov 14;213(12):2553-2565 |
| Submission | Registration date: 8-Sep-2016
Washington University/HHMI |
| Relevance | Model Organism |
Project Data:
| Resource Name | Number
of Links |
|---|
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| GEO DataSets | 1 |
GEO Data Details| Parameter | Value |
|---|
| Data volume, Spots | 181050 |
| Data volume, Processed Mbytes | 3 |
| Data volume, Supplementary Mbytes | 24 |