See
Genome Information for Rattus norvegicus
RNA sequencing of nucleus pulposus cells transduced with control or TonEBP shRNA and cultured under hypertonic conditions
Overall design: Total mRNA was collected from primary nucleus pulposus cells (both control and TonEBP knockdown cells and subjected to RNA sequencing, n=4 for both experimental groups
| Accession | PRJNA342179; GEO: GSE86552 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Rattus norvegicus[Taxonomy ID: 10116] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus; Rattus norvegicus |
| Publications | - Silagi ES et al., "Bicarbonate Recycling by HIF-1-Dependent Carbonic Anhydrase Isoforms 9 and 12 Is Critical in Maintaining Intracellular pH and Viability of Nucleus Pulposus Cells.", J Bone Miner Res, 2018 Feb;33(2):338-355
- Johnson ZI et al., "RNA Sequencing Reveals a Role of TonEBP Transcription Factor in Regulation of Pro-inflammatory Genes in Response to Hyperosmolarity in Healthy Nucleus Pulposus Cells: A HOMEOSTATIC RESPONSE?", J Biol Chem, 2016 Dec 23;291(52):26686-26697
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| Submission | Registration date: 7-Sep-2016
511 College Bldg., Orthopaedic Surgery, Thomas Jefferson University |
| Relevance | Model Organism |
Project Data:
| Resource Name | Number
of Links |
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| Sequence data |
| SRA Experiments | 8 |
| Publications |
| PubMed | 2 |
| PMC | 2 |
| Other datasets |
| BioSample | 8 |
| GEO DataSets | 1 |