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Accession: PRJNA341702 ID: 341702

Homo sapiens (human)

MYC favors the onset of tumorigenesis by inducing epigenetic reprogramming of mammary epithelial cells towards a stem cell-like state [microarray]

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This project is a component of the MYC favors the onset of tumorigenesis by inducing epigenetic reprogramming of mammary epithelial cells towards a stem cell-like state
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1 additional project is a component of the MYC favors the onset of tumorigenesis by inducing epigenetic reprogramming of mammary epithelial cells towards a stem cell-like state.
66644 additional projects are related by organism.
We address the molecular mechanisms through which MYC promotes loss of cell identity and acquisition of stem cell-like traits, favouring the onset of tumorigenesis, by performing gene expression profile analyses in a transition from WT IMEC, IMEC over-expressing MYC and mammospeheres formed from IMEC-MYC (named M2). More...
AccessionPRJNA341702; GEO: GSE86407
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsPoli V et al., "MYC-driven epigenetic reprogramming favors the onset of tumorigenesis by inducing a stem cell-like state.", Nat Commun, 2018 Mar 9;9(1):1024
SubmissionRegistration date: 2-Sep-2016
Chromatin Biology & Epigenetics, Cellular, Computation and Integrative Biology (CIBIO), University of Trento
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Publications
PubMed1
PMC1
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots851670
Data volume, Processed Mbytes25
Data volume, Supplementary Mbytes35

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