Homo sapiens (ID 341575) - BioProject

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Accession: PRJNA341575 ID: 341575

Homo sapiens (human)

See Genome Information for Homo sapiens

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1 additional project is a component of the A new axis linking diabetes to cancer: Glucose regulates tumor suppressor TET2 and 5hmC through AMPK.

We report that high glucose can have a detrimental effect on the stability of TET2 protein, and thereby reduce the genome-wide 5hmC content. More...

Accession	PRJNA341575; GEO: GSE86375
Data Type	Epigenomics
Scope	Multiisolate
Organism	Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
Publications	Wu D et al., "Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer.", Nature, 2018 Jul;559(7715):637-641
Submission	Registration date: 2-Sep-2016 Shi Lab, Endocrinology, The Brigham and Women's Hospital
Relevance	Medical

Project Data:

Parameter	Value
Data volume, Supplementary Mbytes	1363

Parameter	Value
Data volume, Gbases	10
Data volume, Mbytes	4351

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