This SuperSeries is composed of the SubSeries listed below.
Overall design: Refer to individual Series
| Accession | PRJNA341572; GEO: GSE86376 |
| Type | Umbrella project |
| Publications | Wu D et al., "Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer.", Nature, 2018 Jul;559(7715):637-641 |
| Submission | Registration date: 2-Sep-2016
Shi Lab, Endocrinology, The Brigham and Women's Hospital |
| Relevance | Superseries |
Project Data:
| Resource Name | Number
of Links |
|---|
| Sequence data |
| SRA Experiments | 6 |
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| BioSample | 6 |
| GEO DataSets | 3 |
GEO Data Details| Parameter | Value |
|---|
| Data volume, Spots | 328050 |
| Data volume, Processed Mbytes | 5 |
| Data volume, Supplementary Mbytes | 1388 |
| Parameter | Value |
|---|
| Data volume, Gbases | 10 |
| Data volume, Mbytes | 4351 |
A new axis linking diabetes to cancer: Glucose regulates tumor suppressor TET2 and 5hmC through AMPK encompasses the following 2 sub-projects:
| Project Type | Number of Projects |
| Epigenomics | 1 |
BioProject
accession | Organism | Title |
|---|
| PRJNA341575 | Homo sapiens | Change of 5hmC and 5mC landscapes in A2058-TET2WT cells cultured in high-g and normal-g (Shi Lab, Endocrinology, The...) |
|
| Transcriptome or Gene expression | 1 |
BioProject
accession | Organism | Title |
|---|
| PRJNA339942 | Homo sapiens | Expression data of A2058-TET2WT, A2058-TET2M, and Mock cells treated under high-g and normal-g (Shi Lab, Endocrinology, The...) |
|