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Accession: PRJNA340019 ID: 340019

Mus musculus (house mouse)

Expression data from mouse lung alveolar epithelial type II cell with Yap/Taz deletion after bacterial pneumonia-induced lung injury

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47588 additional projects are related by organism.
To define the role of Yap/Taz in alveolar epithelial regeneration, we deleted Yap/Taz in mouse lung Spc-expressing ATII cells by using Spc-CreERT2, Yap fl/fl, Taz fl/fl, R26R-mTmG mice. More...
AccessionPRJNA340019; GEO: GSE86027
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsLaCanna R et al., "Yap/Taz regulate alveolar regeneration and resolution of lung inflammation.", J Clin Invest, 2019 Apr 15;129(5):2107-2122
Grants
  • "miRNAs regulate lung epithelial progenitor cells in development and injury repair" (Grant ID R00 HL111348, National Heart, Lung and Blood Institute)
  • "Regulation of distal lung epithelial regeneration by microRNA-Hippo pathway" (Grant ID R01 HL132115, National Heart, Lung and Blood Institute)
SubmissionRegistration date: 24-Aug-2016
Pharmacology, Center for Translational Medicine, Lewis Katz School of Medicine at Temple University
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Publications
PubMed1
PMC1
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots165380
Data volume, Processed Mbytes3
Data volume, Supplementary Mbytes40

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