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Genome Information for Homo sapiens
We sequenced mRNA from 12 human cancer cell lines treated with DMSO or AZD5153 for 24h to determine compound mechanism of action
Overall design: Measured mRNA levels in cell lines treated with either AZD5153 or DMSO for 24h
| Accession | PRJNA339566; GEO: GSE85840 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
| Publications | Rhyasen GW et al., "AZD5153: A Novel Bivalent BET Bromodomain Inhibitor Highly Active against Hematologic Malignancies.", Mol Cancer Ther, 2016 Nov;15(11):2563-2574 |
| Submission | Registration date: 19-Aug-2016 AstraZeneca |
| Relevance | Medical |
Project Data:
| Resource Name | Number of Links |
|---|
| Sequence data |
| SRA Experiments | 48 |
| Publications |
| PubMed | 1 |
| Other datasets |
| BioSample | 48 |
| GEO DataSets | 1 |