Display Settings:

Format

Send to:

Choose Destination
Accession: PRJNA339566 ID: 339566

Homo sapiens (human)

Transcriptional changes induced by Brd4 inhibitor, AZD5153, in cancer cell lines

See Genome Information for Homo sapiens
We sequenced mRNA from 12 human cancer cell lines treated with DMSO or AZD5153 for 24h to determine compound mechanism of action Overall design: Measured mRNA levels in cell lines treated with either AZD5153 or DMSO for 24h
AccessionPRJNA339566; GEO: GSE85840
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsRhyasen GW et al., "AZD5153: A Novel Bivalent BET Bromodomain Inhibitor Highly Active against Hematologic Malignancies.", Mol Cancer Ther, 2016 Nov;15(11):2563-2574
SubmissionRegistration date: 19-Aug-2016
AstraZeneca
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments48
Publications
PubMed1
Other datasets
BioSample48
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes4
SRA Data Details
ParameterValue
Data volume, Gbases88
Data volume, Mbytes57859

Supplemental Content

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center