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Accession: PRJNA339495 ID: 339495

Mus musculus (house mouse)

De novo DNA methylation by DNA Methyltransferase 3a controls early effector CD8+ T cell fate decisions following activation

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47588 additional projects are related by organism.
DNMT3a is a de novo DNA methyltransferase expressed robustly after T cell activation that regulates plasticity of CD4+ T cell cytokine expression. More...
AccessionPRJNA339495; GEO: GSE85823
Data TypeEpigenomics
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsLadle BH et al., "De novo DNA methylation by DNA methyltransferase 3a controls early effector CD8+ T-cell fate decisions following activation.", Proc Natl Acad Sci U S A, 2016 Sep 20;113(38):10631-6
Grants
  • "Digestive Health Center: Bench to Bedside Research in Pediatric Digestive Disease: Digestive Health Center: Bench to Bedside Research in Pediatric Digestive Diseas: Digestive Health Center: Bench to Bedside Research in Pediatric Digestive Diseas: Digestive Health Center: Bench to Bedside Research in Pediatric Digestive Diseas: Digestive Health Center: Bench to Bedside Research in Pediatric Digestive Diseas: Digestive Health Center: Bench to Bedside Research in Pediatric Digestive Disease: Digestive Health Center: Bench to Bedside Research in Pediatric Digestive Disease" (Grant ID P30 DK078392, National Institute of Diabetes and Digestive and Kidney Diseases)
  • "Cincinnati Center for Excellence in Molecular Hematology" (Grant ID P30 DK090971, National Institute of Diabetes and Digestive and Kidney Diseases)
  • "Regulation of Apoptosis in Activated Primary T cells: Regulation of Apoptosis in Activated Primary T Cells: Regulation of Apoptosis in Activated Primary T Cells: Regulation of Apoptosis in Activated Primary T Cells: Regulation of Apoptosis in Activated Primary T Cells: Regulation of Apoptosis in Activated Primary T Cells: Regulation of Apoptosis in Activated Primary T Cells" (Grant ID R01 AI057753, National Institute of Allergy and Infectious Diseases Extramural Activities)
  • "Exploiting the DNA damage response to selectively sculpt the T cellrepertoire" (Grant ID R01 AI109810, National Institute of Allergy and Infectious Diseases Extramural Activities)
  • "Inhibition of DNA methylation to prevent tumor-induced immune tolerance" (Grant ID K08 HL108346, National Heart, Lung, and Blood Institute)
  • "REGIONAL ONCOLOGY RESEARCH CENTER: Regional Oncology Research Center: REGIONAL ONCOLOGY RESEARCH CENTER: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center: Regional Oncology Research Center" (Grant ID P30 CA006973, National Cancer Institute)
SubmissionRegistration date: 18-Aug-2016
Gamper Lab, Oncology, Johns Hopkins University
RelevanceModel Organism
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments12
Publications
PubMed1
PMC1
Other datasets
BioSample12
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes1416
SRA Data Details
ParameterValue
Data volume, Gbases26
Data volume, Mbytes18780

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