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3 additional projects are components of the Cellular model of colon cancer progression reveals signatures of mRNAs, miRNA, lncRNAs and epigenetic modifications associated with metastasis..
H3K4me3, H3K27me3, and H3K79me3 profiling of a cellular model of colorectal cancer progression, which is based on four defined derivates of a CRC cell line that resulted from EMT/MET transitions and phenotypically recapitulate the metastatic cascade: epithelial-like primary tumor, mesenchymal-like tumor cells growing in soft agar or as colonospheres, and mouse xenografts of the latter resulting in lung-metastasis comprised of epithelial-state cells.
Overall design: H3K4me3, H3K27me3, and H3K79me3
| Accession | PRJNA339293; GEO: GSE85766 |
| Data Type | Epigenomics |
| Scope | Multiisolate |
| Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
| Publications | Rokavec M et al., "Cellular Model of Colon Cancer Progression Reveals Signatures of mRNAs, miRNA, lncRNAs, and Epigenetic Modifications Associated with Metastasis.", Cancer Res, 2017 Apr 15;77(8):1854-1867 |
| Submission | Registration date: 17-Aug-2016
Hermeking, Institute of Pathology, Ludwig-Maximilians-University Munich |
| Relevance | Medical |
Project Data:
| Resource Name | Number
of Links |
|---|
| Sequence data |
| SRA Experiments | 12 |
| Publications |
| PubMed | 1 |
| Other datasets |
| BioSample | 12 |
| GEO DataSets | 1 |