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Accession: PRJNA338878 ID: 338878

Homo sapiens (human)

Novel ABCG2 antagonists to reverse topotecan-mediated chemotherapeutic resistance in ovarian carcinoma xenografts.

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In order to address the treatment difficulties associated with chemotherapetic resistance in ovarian cancer, we combined our compounds with topotecan and admininstered the mixture to chemoresistant Igrov1/T8 ovarian cancer cells in vitro and Igrov1/T8 xenografts in CB-17 SCID mice. More...
AccessionPRJNA338878; GEO: GSE85582
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsRicci JW et al., "Novel ABCG2 Antagonists Reverse Topotecan-Mediated Chemotherapeutic Resistance in Ovarian Carcinoma Xenografts.", Mol Cancer Ther, 2016 Dec;15(12):2853-2862
SubmissionRegistration date: 14-Aug-2016
CTSC 3120, Office of Research, University of New Mexico
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Publications
PubMed1
PMC1
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots214468
Data volume, Processed Mbytes3
Data volume, Supplementary Mbytes35

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