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Accession: PRJNA338632 ID: 338632

Homo sapiens (human)

Effects of IFN-a and IFN-b on ex vivo ATL patient pbmcs

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The data contained in this record are used to differentiate between the effects of IFN-a and IFN-b on 48h cultures of the ex vivo pbmcs of ATL patients, using Affymetrix microarrays (HuGene 1. More...
AccessionPRJNA338632; GEO: GSE85487
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
Publications
  • Khouri R et al., "A genetic IFN/STAT1/FAS axis determines CD4 T stem cell memory levels and apoptosis in healthy controls and Adult T-cell Leukemia patients.", Oncoimmunology, 2018;7(5):e1426423
  • Dierckx T et al., "IFN-β induces greater antiproliferative and proapoptotic effects and increased p53 signaling compared with IFN-α in PBMCs of Adult T-cell Leukemia/Lymphoma patients.", Blood Cancer J, 2017 Jan 27;7(1):e519
SubmissionRegistration date: 11-Aug-2016
Clinical and Epidemiological Virology, Microbiology and Immunology, KU Leuven
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Publications
PubMed2
PMC2
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots665940
Data volume, Processed Mbytes13
Data volume, Supplementary Mbytes82

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