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Accession: PRJNA338631 ID: 338631

Homo sapiens (human)

Regulation of stem cell maintenance and lymphoid specification by the ubiquitin ligase Huwe1

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66644 additional projects are related by organism.
The ubiquitin ligase Huwe1 regulates stem cell quiescence, maintenance and lymphoid specification by controlling the expression of N-Myc. More...
AccessionPRJNA338631; GEO: GSE85488
Data TypeEpigenomics
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsKing B et al., "The ubiquitin ligase Huwe1 regulates the maintenance and lymphoid commitment of hematopoietic stem cells.", Nat Immunol, 2016 Nov;17(11):1312-1321
Grants
  • "preTCR as an inducer of cell survival and transformation: Regulation of hematopoietic stem cell differentiation: Regulation of hematopoietic stem cell differentiation: preTCR as an inducer of cell survival and transformation: Regulation of hematopoietic stem cell differentiation: Regulation of hematopoietic stem cell differentiation: Regulation of hematopoietic stem cell differentiation: Regulation of hematopoietic stem cell differentiation" (Grant ID R01 CA105129, National Cancer Institute)
  • "The role of the SCF/FBW7 ubiquitin ligase complex in hematopiesis and leukemia: The role of the SCF/FBW7 ubiquitin ligase complex in hematopiesis and leukemia.: The role of the SCF/FBW7 ubiquitin ligase complex in hematopiesis and leukemia.: The role of the SCF/FBW7 ubiquitin ligase complex in hematopiesis and leukemia.: The role of the SCF/FBW7 ubiquitin ligase complex in hematopiesis and leukemia: The role of the SCF/FBW7 ubiquitin ligase complex in hematopiesis and leukemia: The role of the SCF/FBW7 ubiquitin ligase complex in hematopiesis and leukemia" (Grant ID R01 CA133379, National Cancer Institute)
  • "Mechanisms of T cell leukemia induction and maintenance" (Grant ID R01 CA149655, National Cancer Institute)
  • "Genetic Dissection of Acute Myeloid Leukemia." (Grant ID R01 CA169784, National Cancer Institute)
  • "Role of TET2 mutations in malignant transformation and acute myeloid leukemia" (Grant ID R01 CA173636, National Cancer Institute)
SubmissionRegistration date: 11-Aug-2016
Aifantis Lab, Pathology, NYU School of Medicine
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments8
Publications
PubMed1
PMC1
Other datasets
BioSample8
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes332
SRA Data Details
ParameterValue
Data volume, Gbases4
Data volume, Mbytes1741

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