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Genome Information for Mus musculus
To test if mitotic chromosomes have decreased accessibility, we utilized Assay for Transposase-Accessible Chromatin using sequencing (ATAC-seq) analysis where the integration of sequencing-compatible adaptors by the Tn5 transposase is directly correlated with the accessibility of genomic regions
Overall design: We performed ATAC-seq in 50,000 asynchronous cells as well as 50,000 Nocodazole-synchronized mitotic cells in two biological replicates each.
| Accession | PRJNA336477; GEO: GSE85184 |
| Data Type | Epigenomics |
| Scope | Multiisolate |
| Organism | Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus |
| Publications | Teves SS et al., "A dynamic mode of mitotic bookmarking by transcription factors.", Elife, 2016 Nov 19;5 |
| Submission | Registration date: 4-Aug-2016
Tjian, Molecular Cell Biology, UC Berkeley |
| Relevance | Model Organism |
Project Data:
| Resource Name | Number
of Links |
|---|
| Sequence data |
| SRA Experiments | 4 |
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| BioSample | 4 |
| GEO DataSets | 1 |