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Accession: PRJNA336381 ID: 336381

Homo sapiens (human)

MEK inhibition rewires enhancer landscapes in RAS-driven Rhabdomyosarcoma to unlock a myogenic differentation block

See Genome Information for Homo sapiens
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This project is a component of the Epigenetic Reprogramming of mutant RAS-driven Rhabdomyosarcoma via MEK Inhibition
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2 additional projects are components of the Epigenetic Reprogramming of mutant RAS-driven Rhabdomyosarcoma via MEK Inhibition.
66644 additional projects are related by organism.
Trametinib-treated rhabdomyosarcoma cells undergo transcriptional reprogramming akin to myogenic differentiation. More...
AccessionPRJNA336381; GEO: GSE85170
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsYohe ME et al., "MEK inhibition induces MYOG and remodels super-enhancers in RAS-driven rhabdomyosarcoma.", Sci Transl Med, 2018 Jul 4;10(448)
SubmissionRegistration date: 3-Aug-2016
Javed Khan, Genetics Branch, NCI, NIH
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments18
Publications
PubMed1
PMC1
Other datasets
BioSample18
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes14
SRA Data Details
ParameterValue
Data volume, Gbases64
Data volume, Mbytes40287

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