Sign in to NCBI

Display Settings:

Format

Send to:

Choose Destination
Accession: PRJNA336374 ID: 336374

Homo sapiens (human)

MEK inhibition profoundly reprograms myogenic super enhancers in mutant-RAS driven Rhabdomyosarcoma

See Genome Information for Homo sapiens
Navigate Up
This project is a component of the Epigenetic Reprogramming of mutant RAS-driven Rhabdomyosarcoma via MEK Inhibition
Navigate Across
2 additional projects are components of the Epigenetic Reprogramming of mutant RAS-driven Rhabdomyosarcoma via MEK Inhibition.
66644 additional projects are related by organism.
Trametinib-treated rhabdomyosarcoma cells undergo transcriptional reprogramming akin to myogenic differentiation. More...
AccessionPRJNA336374; GEO: GSE85169
Data TypeEpigenomics
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsYohe ME et al., "MEK inhibition induces MYOG and remodels super-enhancers in RAS-driven rhabdomyosarcoma.", Sci Transl Med, 2018 Jul 4;10(448)
SubmissionRegistration date: 3-Aug-2016
Javed Khan, Genetics Branch, NCI, NIH
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments38
Publications
PubMed1
PMC1
Other datasets
BioSample38
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes11
SRA Data Details
ParameterValue
Data volume, Gbases118
Data volume, Mbytes45425

Supplemental Content

Related information

Recent activity

Clear Turn Off Turn On
  • Blood DNA methylation profiles from first episode psychosis patients and control...
    Blood DNA methylation profiles from first episode psychosis patients and controls I
    Blood DNA methylation profiles from first episode psychosis patients and controls I
    BioProject
  • Homo sapiens
    Homo sapiens
    MEK inhibition profoundly reprograms myogenic super enhancers in mutant-RAS driven Rhabdomyosarcoma
    BioProject
  • Escherichia coli
    Escherichia coli
    Escherichia coli K-12: 0%, 10% and 30% hydrogen peroxide (H2O2) treatments, in wild type and luxS mutants
    BioProject
  • Olpidium sp. strain:OlpTTP4mda3long_152
    Olpidium sp. strain:OlpTTP4mda3long_152
    Olpidium sp. strain:OlpTTP4mda3long_152 Genome sequencing
    BioProject
  • Sus scrofa
    Sus scrofa
    Longissimus dorsi muscle transcriptome in pure and crossbred Iberian pigs at birth and growing stages
    BioProject

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
You are here: NCBI
Support Center