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Genome Information for Homo sapiens
The Amish and Hutterites are U.S. farming populations with remarkably similar lifestyles.
More...The Amish and Hutterites are U.S. farming populations with remarkably similar lifestyles. However, the Amish follow traditional farming practices, while the Hutterites employ modern farming techniques, and also show striking differences in asthma prevalence. Little is known about immune responses underlying these differences. To address this, we measured environmental exposures, genetic ancestry, and immune profiles in 60 Amish and Hutterite schoolchildren. We further collected indoor house dust to measure allergen, endotoxin, and microbiome composition, and immune and airway responses to house dust extract were tested in murine models of experimental allergic asthma.
Less...| Accession | PRJNA335766 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
| Grants | - "Genomic Studies of Sex-Specific Architecture of Asthma-Associated Traits: Sex-Specific Genetic Architecture of Asthma-Associated Quantitative Traits" (Grant ID R01 HL085197, National Heart, Lung, and Blood Institute)
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| Submission | Registration date: 28-Jul-2016
University of Chicago |
| Relevance | Medical |
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