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Accession: PRJNA292398 ID: 292398

Homo sapiens (human)

Identification of MITF-regulated genes in the human melanoma cell line Ma-Mel-15

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We analyzed the transcriptional response of the human melanoma cell line Ma-Mel-15 either transfected with control siRNA (siNT = non-targeting siRNA) or transfected with siRNAs (pool of 4 active and independent siRNAs) directed against the melanocytic transcription factor and lineage oncogene MITF (Microphthalmia-associated transcription factor). More...
AccessionPRJNA292398; GEO: GSE71881
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsRiesenberg S et al., "MITF and c-Jun antagonism interconnects melanoma dedifferentiation with pro-inflammatory cytokine responsiveness and myeloid cell recruitment.", Nat Commun, 2015 Nov 4;6:8755
SubmissionRegistration date: 10-Aug-2015
RNA Biology, Institute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn
RelevanceMedical
Project Data:
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PubMed1
PMC1
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots189256
Data volume, Processed Mbytes6
Data volume, Supplementary Mbytes1

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