This SuperSeries is composed of the SubSeries listed below.
Overall design: Refer to individual Series
| Accession | PRJNA292064; GEO: GSE71780 |
| Type | Umbrella project |
| Publications | Gilan O et al., "Functional interdependence of BRD4 and DOT1L in MLL leukemia.", Nat Struct Mol Biol, 2016 Jul;23(7):673-81 |
| Submission | Registration date: 6-Aug-2015
Peter MacCallum Cancer Centre |
| Relevance | Superseries |
Project Data:
| Resource Name | Number
of Links |
|---|
| Sequence data |
| SRA Experiments | 63 |
| Publications |
| PubMed | 1 |
| Other datasets |
| BioSample | 63 |
| GEO DataSets | 7 |
Functional interdependency of BRD4 and DOT1L in MLL leukaemia encompasses the following 6 sub-projects:
| Project Type | Number of Projects |
| Epigenomics | 2 |
BioProject
accession | Organism | Title |
|---|
| PRJNA292067 | Homo sapiens | ChIPSeq of MV4;11 cell treated with DMSO, I-BET, SGC0946 and combination of I-BET and SGC0946 (Peter MacCallum Cancer Centre) | | PRJNA292068 | Homo sapiens | ChIPSeq of MV4;11 cell treated with SGC0946 for 8 hours and washout (Peter MacCallum Cancer Centre) |
|
| Transcriptome or Gene expression | 4 |
BioProject
accession | Organism | Title |
|---|
| PRJNA292066 | Homo sapiens | RNASeq of MV4;11 cell treated with DMSO, I-BET, SGC0946 and combination of I-BET and SGC0946 (Peter MacCallum Cancer Centre) | | PRJNA320733 | Homo sapiens | RNASeq of MV4;11 cells transduced with scramble shRNA or BRD4 shRNA in combination with DMSO or SGC0946 (Peter MacCallum Cancer Centre) | | PRJNA320734 | Homo sapiens | RNASeq of 4SU labelled nascent RNA in MV4;11 cell treated with DMSO, I-BET, SGC0946 and combination of I-BET and SGC0946 (Peter MacCallum Cancer Centre) | | PRJNA320736 | Mus musculus | RNASeq of MLL-AF9 cells transduced with scramle shRNA or BRD4 shRNA in combination with DMSO or SGC0946 (Peter MacCallum Cancer Centre) |
|