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Accession: PRJNA291978 ID: 291978

Homo sapiens (human)

Inhibitors of the histone lysine demethylase KDM1A are broadly efficacious in AML by evicting the enzyme from chromatin [RNA-Seq]

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This project is a component of the Inhibitors of the histone lysine demethylase KDM1A are broadly efficacious in AML by evicting the enzyme from chromatin
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1 additional project is a component of the Inhibitors of the histone lysine demethylase KDM1A are broadly efficacious in AML by evicting the enzyme from chromatin.
66643 additional projects are related by organism.
Investigating the effects of two different classes of KDM1A inhibitors on the transcriptome of AML cell lines Overall design: 16 different samples with biological replicates. More...
AccessionPRJNA291978; GEO: GSE71740
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsMcGrath JP et al., "Pharmacological Inhibition of the Histone Lysine Demethylase KDM1A Suppresses the Growth of Multiple Acute Myeloid Leukemia Subtypes.", Cancer Res, 2016 Apr 1;76(7):1975-88
SubmissionRegistration date: 5-Aug-2015
Constellation Pharmaceuticals
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments32
Publications
PubMed1
Other datasets
BioSample32
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes3
SRA Data Details
ParameterValue
Data volume, Gbases110
Data volume, Mbytes69467

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