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Genome Information for Homo sapiens
We evaluated changes in mRNA stability and transcription using 4sU metabolic pulse labeling across a four hour time course following activation of Jurkat T cells with PMA and PHA
Overall design: Measurement of total mRNA (T) and 4sU labeled mRNA (IP) in three biological replicates at five time points: prior to activation (U) and the first four hours after activation (1-4)
| Accession | PRJNA291072; GEO: GSE71382 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
| Publications | Blackinton JG et al., "Functional coordination and HuR-mediated regulation of mRNA stability during T cell activation.", Nucleic Acids Res, 2016 Jan 8;44(1):426-36 |
| Submission | Registration date: 27-Jul-2015
Keene Lab, Molecular Genetics and Microbiology, Duke University |
| Relevance | Medical |
Project Data:
| Resource Name | Number
of Links |
|---|
| Sequence data |
| SRA Experiments | 28 |
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| BioSample | 28 |
| GEO DataSets | 1 |