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Genome Information for Homo sapiens
We performed a comprehensive molecular and cellular analysis of primary dermal fibroblasts taken from a patient with recurrent cancers, harboring a BRCA1 mosaic epimutation (BRCA1mosMe) in comparison to their isogenic control fibroblasts (BRCA1wt), taken from the patient´s healthy monozygous sister.
Overall design: 4 independent samples per individual
| Accession | PRJNA290317; GEO: GSE71078 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
| Publications | Etzold A et al., "CAF-like state in primary skin fibroblasts with constitutional BRCA1 epimutation sheds new light on tumor suppressor deficiency-related changes in healthy tissue.", Epigenetics, 2016;11(2):120-31 |
| Submission | Registration date: 20-Jul-2015
Universität Mainz |
| Relevance | Medical |
Project Data:
| Resource Name | Number
of Links |
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| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| GEO DataSets | 1 |
GEO Data Details| Parameter | Value |
|---|
| Data volume, Spots | 395088 |
| Data volume, Processed Mbytes | 9 |
| Data volume, Supplementary Mbytes | 20 |