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Accession: PRJNA290206 ID: 290206

Homo sapiens (human)

ACTG A5258 Clinical administration of chloroquine to patients with untreated chronic HIV infection to reduce immune activation

See Genome Information for Homo sapiens
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This project is a component of the Clinical administration of chloroquine to HIV-infected patients that are untreated or receiving antiretroviral therapy
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1 additional project is a component of the Clinical administration of chloroquine to HIV-infected patients that are untreated or receiving antiretroviral therapy.
66644 additional projects are related by organism.
ACTG A5258, we asked whether chloroquine could reduce the immune activation in HIV infection posited to be driven by microbial TLR agonists, such as bacterial elements translocated from the gut and HIV-1 RNAs . More...
AccessionPRJNA290206; GEO: GSE71063
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsJacobson JM et al., "The Effect of Chloroquine on Immune Activation and Interferon Signatures Associated with HIV-1.", AIDS Res Hum Retroviruses, 2016 Jul;32(7):636-47
SubmissionRegistration date: 17-Jul-2015
Genomics Core, Developmental and Cognitive Neuroscience, Yerkes National Primate Research Center
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Publications
PubMed1
PMC1
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots2187000
Data volume, Processed Mbytes40
Data volume, Supplementary Mbytes198

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