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Accession: PRJNA289569 ID: 289569

Homo sapiens (human)

Profiles of ribosome-associated mRNAs regulated by expression of wild-type (WT) or R534H variant of DDX3 with or without Sodium Arsenite treatment [Ribo-Seq]

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This project is a component of the Profiles of ribosome-associated mRNAs regulated by expression of wild-type (WT) or R534H variant of DDX3 with or without Sodium Arsenite treatment
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2 additional projects are components of the Profiles of ribosome-associated mRNAs regulated by expression of wild-type (WT) or R534H variant of DDX3 with or without Sodium Arsenite treatment.
66644 additional projects are related by organism.
By using ribosome profiling, we demonstrate that catalytic activity of the RNA helicase DDX3 is generally required for mediating translation repression under stress. More...
AccessionPRJNA289569; GEO: GSE70802
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsOh S et al., "Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress.", Oncotarget, 2016 May 10;7(19):28169-82
SubmissionRegistration date: 11-Jul-2015
Neurology and Neurological Sciences, Stanford University School of Medicine
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments12
Publications
PubMed1
PMC1
Other datasets
BioSample12
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes255
SRA Data Details
ParameterValue
Data volume, Gbases16
Data volume, Mbytes10231

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