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Accession: PRJNA289489 ID: 289489

Homo sapiens (human)

Differential expression profiles of type I JAK inhibitor persistent vs. naïve MPN cells

See Genome Information for Homo sapiens
The type I JAK inhibitor ruxolitinib is approved for therapy of MPN patients but evokes resistance with longer exposure. More...
AccessionPRJNA289489; GEO: GSE69827
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsMeyer SC et al., "CHZ868, a Type II JAK2 Inhibitor, Reverses Type I JAK Inhibitor Persistence and Demonstrates Efficacy in Myeloproliferative Neoplasms.", Cancer Cell, 2015 Jul 13;28(1):15-28
SubmissionRegistration date: 12-Jun-2015
Genomics Core, Memorial Sloan Kettering Cancer Center
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments24
Publications
PubMed1
PMC1
Other datasets
BioSample24
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes3
SRA Data Details
ParameterValue
Data volume, Gbases95
Data volume, Mbytes74777

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