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Accession: PRJNA288457 ID: 288457

Mus musculus (house mouse)

Nurr1 and Retinoid X Receptor ligands stimulate Ret signaling in dopamine neurons and can alleviate α-synuclein disrupted gene expression

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47588 additional projects are related by organism.
We ovexpressed human alpha synuclein alone or together with Nurr1 in mouse primary midbrain cultures and identified the full spectrum of genes whose expression is affected by alpha synuclein, including genes whose expression is normalized after Nurr1 overexpression. More...
AccessionPRJNA288457; GEO: GSE70368
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismMus musculus[Taxonomy ID: 10090]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
PublicationsVolakakis N et al., "Nurr1 and Retinoid X Receptor Ligands Stimulate Ret Signaling in Dopamine Neurons and Can Alleviate α-Synuclein Disrupted Gene Expression.", J Neurosci, 2015 Oct 21;35(42):14370-85
SubmissionRegistration date: 29-Jun-2015
LICR
RelevanceModel Organism
Project Data:
Resource NameNumber
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Sequence data
SRA Experiments19
Publications
PubMed1
PMC1
Other datasets
BioSample19
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes5
SRA Data Details
ParameterValue
Data volume, Gbases12
Data volume, Mbytes11791

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