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Accession: PRJNA288298 ID: 288298

Homo sapiens (human)

Comparison of the Transcriptional Profiles of Melanocytes from Dark and Light Skinned Individuals under Basal Conditions and Following Ultraviolet-B Irradiation

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We analysed the whole-genome transcriptional profile of 6 cell lines of dark melanocytes (DM) and 6 of light melanocytes (LM) at basal conditions and after UVB at different time points (6, 12 and 24h) to investigate the mechanisms by which melanocytes protect human skin from the damaging effects of ultraviolet-B radiation (UVB). More...
AccessionPRJNA288298; GEO: GSE70280
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
Publications
  • López S et al., "Expression profiling of human melanocytes in response to UV-B irradiation.", Genom Data, 2015 Dec;6:195-6
  • López S et al., "Comparison of the Transcriptional Profiles of Melanocytes from Dark and Light Skinned Individuals under Basal Conditions and Following Ultraviolet-B Irradiation.", PLoS One, 2015;10(8):e0134911
SubmissionRegistration date: 25-Jun-2015
UCL
RelevanceMedical
Project Data:
Resource NameNumber
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Publications
PubMed2
PMC2
Other datasets
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Spots2172426
Data volume, Processed Mbytes53
Data volume, Supplementary Mbytes251

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