BioProject

Layer peritonitis is considered a major cause of morbidity and mortality in laying hens which leads to significant economic losses to the egg industry worldwide. More...

Layer peritonitis is considered a major cause of morbidity and mortality in laying hens which leads to significant economic losses to the egg industry worldwide. Among the bacterial pathogens, E. coli is the most common bacterial species associated with layer peritonitis. However, the pathogenesis of layer peritonitis has not been elucidated. The objectives of the current study are; 1) to identify potential virulence factors encoded in peritonitis causing E. coli strain using whole genome sequencing, 2) ascertain genotypic homology among avian pathogenic E. coli (APEC) and human extraintestinal pathogenic E. coli (ExPEC) by comparative genomics and 3) to identify potential vaccine targets through antigenome approach Less...