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Accession: PRJNA287319 ID: 287319

Loss of Ring1B catalytic activity causes a pronounced reduction in H3K27me3 deposition yet minimally disrupts the expression of target genes

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series
AccessionPRJNA287319; GEO: GSE69978
TypeUmbrella project
PublicationsIllingworth RS et al., "The E3 ubiquitin ligase activity of RING1B is not essential for early mouse development.", Genes Dev, 2015 Sep 15;29(18):1897-902
SubmissionRegistration date: 18-Jun-2015
Prof. Wendy Bickmore, Human Genetics Unit, MRC
RelevanceSuperseries
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments12
Publications
PubMed1
PMC1
Other datasets
BioSample12
GEO DataSets3
GEO Data Details
ParameterValue
Data volume, Spots501129
Data volume, Processed Mbytes13
Data volume, Supplementary Mbytes876
SRA Data Details
ParameterValue
Data volume, Gbases24
Data volume, Mbytes12279
This project encompasses the following 2 sub-projects:
Project TypeNumber of Projects
Epigenomics1
BioProject
accession
OrganismTitle
PRJNA287271Mus musculusMouse ES cells expressing catalytically inactive Ring1B display impaired Ring1B and H3K27me3 deposition. (Prof. Wendy Bickmore, Human...)
Transcriptome or Gene expression1
BioProject
accession
OrganismTitle
PRJNA286873Mus musculusCatalytically inactive Ring1B maintains near wildtype levels of gene expression in mESCs (Prof. Wendy Bickmore, Human...)

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