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ChIP-seq for the insulator protein CTCF in THP-1 cells after stimulation with the the natural VDR ligand 1,25-dihydroxyvitamin D3 (1,25(OH)2D3)
Overall design: THP-1 cells were treated for 24 h with 100 nM 1,25(OH)2D3 before ChIP assay
| Accession | PRJNA287278; GEO: GSE69962 |
| Data Type | Epigenomics |
| Scope | Multiisolate |
| Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
| Publications (total 3) Less... | - Warwick T et al., "A hierarchical regulatory network analysis of the vitamin D induced transcriptome reveals novel regulators and complete VDR dependency in monocytes.", Sci Rep, 2021 Mar 22;11(1):6518
More...- Warwick T et al., "A hierarchical regulatory network analysis of the vitamin D induced transcriptome reveals novel regulators and complete VDR dependency in monocytes.", Sci Rep, 2021 Mar 22;11(1):6518
- Neme A et al., "Vitamin D-dependent chromatin association of CTCF in human monocytes.", Biochim Biophys Acta, 2016 Nov;1859(11):1380-1388
- Seuter S et al., "Epigenome-wide effects of vitamin D and their impact on the transcriptome of human monocytes involve CTCF.", Nucleic Acids Res, 2016 May 19;44(9):4090-104
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| Submission | Registration date: 17-Jun-2015
Institute of Biomedicine, University of Eastern Finland |
| Relevance | Medical |
Project Data:
| Resource Name | Number
of Links |
|---|
| Sequence data |
| SRA Experiments | 9 |
| Publications |
| PubMed | 3 |
| PMC | 2 |
| Other datasets |
| BioSample | 9 |
| GEO DataSets | 1 |