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Accession: PRJNA287138 ID: 287138

Homo sapiens (human)

Ribosome profiling of MCF10A cells treated with TGFb and esterified leucine

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This project is a component of the Ribosome profiling of TGFb-treated cells indicates reduced leucine availability
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2 additional projects are components of the Ribosome profiling of TGFb-treated cells indicates reduced leucine availability.
66644 additional projects are related by organism.
MCF10A-inducible RASV12 cells were treated with TGF-beta for 48hr. As rescue experiment, in one sample cells were treated with esterified leucine for 18hr. Overall design: 1 replicate per condition
AccessionPRJNA287138; GEO: GSE69922
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsLoayza-Puch F et al., "TGFβ1-induced leucine limitation uncovered by differential ribosome codon reading.", EMBO Rep, 2017 Apr;18(4):549-557
SubmissionRegistration date: 16-Jun-2015
Agami Lab, Gene Regulation, Netherlands Cancer Institute
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Sequence data
SRA Experiments3
Publications
PubMed1
PMC1
Other datasets
BioSample3
GEO DataSets1
GEO Data Details
ParameterValue
Data volume, Supplementary Mbytes40
SRA Data Details
ParameterValue
Data volume, Gbases14
Data volume, Mbytes7841

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