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1 additional project is a component of the The histone H3 lysine 4 presenter WDR5 induces N-Myc target gene transcription and promotes neuroblastoma.
WDR5 is an important co-factor for N-Myc-regulated transcriptional activation and tumorigenesis
We analysed whether WDR5 siRNAs modulate gene expression
Overall design: Neuroblastoma BE(2)-C cells were treated with control siRNA, WDR5 siRNA-1, and WDR5 siRNA-2 for 40 hours, and subjected to differential gene expression studies with Affymetrix microarrays.
| Accession | PRJNA286992; GEO: GSE69861 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
| Submission | Registration date: 15-Jun-2015
Children's Cancer Institute Australia |
| Relevance | Medical |
Project Data:
| Resource Name | Number
of Links |
|---|
| GEO DataSets | 1 |
GEO Data Details| Parameter | Value |
|---|
| Data volume, Spots | 160851 |
| Data volume, Processed Mbytes | 3 |
| Data volume, Supplementary Mbytes | 26 |